Choleslo Review – Is It The Best Cholesterol Lowering Supplement?

Is choleslo the best cholesterol-lowering supplement?


Choleslo is a widely-used over-the-counter cholesterol-lowering supplement. We had second thoughts about confirming its claims since it hasn’t been approved by the FDA, so we took up the task of researching the ingredients, available clinical studies, side effects, and customer reviews.

We then did a summary and wrote a short review of the product.

You can buy choleslo on the manufacturer’s official website

Meanwhile, here’s what you need to know about it.


HFL CholesLo is an OTC supplement that lowers cholesterol levels. It is produced with natural ingredients, like herbs, amino acids, and vitamins. According to the producer, it causes a 30-point drop in your cholesterol level within a 30-day timeline.

Ingredients used for the production of this supplement include:

  • Alpha-lipoic acid
  • Turmeric
  • N-acetyl-l-cysteine (NAC)
  • Milk thistle extract
  • Coenzyme Q10
  • Phytosterols complex
  • Vitamins B5, B6, and B12
  • Folate
  • D-pantethine
  • Guggul lipid extract
  • Garlic powder
  • Policosanol
  • Artichoke 2.5%
  • Mixed tocotrienols
  • Red yeast rice extract.

According to the manufacturers, CholesLo is effective against the six major causes of high cholesterol levels. The product is manufactured in a facility approved by the FDA, and have received a thumbs-up by some renowned physicians like Dr. Spring Cheng, Dr. Steven Chen, Dr. Michael Kaufman, and Dr. Sam Robbins. It is a suitable alternative to medications and prescription drugs.

What are the benefits of choleslo?

The supplement claims to treat one of the primary causes of high cholesterol, like hormonal changes caused by aging. Let’s use red yeast rice for instance. It contains monacolin K. Monacolin K is the active component of Lovastatin (Mevacor). This has been verified by a study published in the Journal Pharmacy & Therapeutics.

Choleslo also has phytosterols. But then, to determine the effectiveness of any product, the ingredient portions must be listed. Unfortunately, the manufacturer of Choleslo has not stated the actual amounts of phytosterols and red yeast rice used in the capsules. 

Is it approved by the FDA?

Choleslo is not approved by the FDA. However, the facility in which it is manufactured is approved by the FDA. The FDA does not regulate this product as it is neither medication nor a drug that treats a specific medical condition.

Side effects

No side effects have been acknowledged on the manufacturer’s website. However, people who have stomach problems should eat before taking this product. After diligent investigations, we found complains about:

  • Nausea
  • Headaches
  • Joint aches
  • Stomach ache

Thus, the pills can cause side effects, though this depends on your body’s response to it. However, almost all dietary supplements cause a few side effects here and there. As for CholesLo, there are no complaints about serious adverse effects or bad reactions.


High blood levels of LDL cholesterol put a person at risk of stroke and heart attack, so you will want to do your possible best to keep your cholesterol at healthy levels.

If your doctor diagnoses you with high cholesterol, they will prescribe statins, a drug that helps to lower cholesterol levels. Your doctor may also recommend dietary changes and changes to your exercise routine. Changes to your diet would include eating foods that help to lower your cholesterol level.

The human body has two kinds of cholesterol:

  • High-density lipoprotein (HDL)
  • Low-density lipoprotein (LDL)

The human body doesn’t need much LDL because it is the “bad” cholesterol. Recommended levels of cholesterol are:

  • HDL cholesterol: not less than 50 mg/dL
  • LDL cholesterol: should be below 100 mg/dL
  • Total cholesterol: less than 200 mg/dL

Your risk for high LDL cholesterol is imminent if you lead a sedentary life or are overweight. Sometimes, the tendency for high cholesterol may be hereditary.

The liver is responsible for the production of cholesterol. You may also get cholesterol from foods that contain it, but mostly from foods that contain trans and saturated fats. These types of fat stimulate the liver to produce more cholesterol.

However, it is important to know that there are foods and even supplements that can help to reduce your cholesterol levels.

If you intend to take any supplement, then you must discuss with your doctor. This is very important for pregnant women.

What causes high cholesterol?

Eating an excess of foods that contain trans fats, saturated fats, and cholesterol may heighten your risk of high cholesterol. You are also at risk if you lead an unhealthy lifestyle, like smoking and living a sedentary life.

Genetics also plays a role in the development of high cholesterol. Parents pass down their genes to their children. Some genes contain codes that instruct your body on how it can process fats and cholesterol. So, if your parents have cholesterol problems, there are chances that you too may have it.

Sometimes, high cholesterol may be caused by familial hypercholesterolemia. It is a genetic condition that stops the removal of LDL from your body. a study by the National Human Genome Research Institute has found out that most adults who have familial hypercholesterolemia have total cholesterol levels exceeding 300 mg/dL. Their LDL levels exceed 200 mg/dL.

Some underlying health conditions may increase your risk of having high cholesterol and associated complications. Examples are hypothyroidism and diabetes.

What are the effects of high cholesterol on the body?

Cholesterol on its own isn’t bad. Without cholesterol, your body will find it hard to make vitamin D, digestive fluids, and hormones. It also enhances the proper functioning of your organs.

However, excess cholesterol can cause some health problems. High blood levels of LDL cholesterol can cause damage to your arteries, heighten your risk for a stroke, and even trigger heart diseases. You can improve the quality of life and decrease complications associated with heart disease by going for regular cholesterol checks. Other factors that might help you reduce the risk of high cholesterol include lifestyle changes, diet, exercise, and medications.

Circulatory and cardiovascular systems

When you have excess LDL cholesterol in your blood, it will accumulate in your arteries, clog, and reduce their flexibility. Atherosclerosis is a condition characterized by the hardening of your arteries. Blood fails to flow properly and so your heart is forced to do more work to push blood through these arteries. With time, the plaque will build up in your arteries, and cause heart disease. 

A build-up of plaque in the coronary arteries can impede the flow of blood to the muscles of your heart, and when your heart muscles are deprived of oxygen-rich blood, you experience chest called angina. Note that angina is not a heart attack. It is just a temporary stoppage of blood flow. It means that you may be at risk for a heart attack. Sometimes, a small piece of plaque can break off and form a clot, your artery may narrow continually until it eventually blocks the blood supply to your heart, thus resulting in a heart attack. If this happens in the arteries that supply the brain or arteries within the brain, then it may result in a stroke.

A plaque can impede blood flow to the arteries supplying the feet, legs, and intestinal tract. This condition is known as a peripheral arterial disease (PAD).

Endocrine system

The glands that produce hormones in your body use cholesterol to produce hormones such as cortisol, testosterone, and estrogen. Hormones also affect your body’s cholesterol levels. Studies have shown that during menstruation, women experience a rise in their estrogen levels. HDL cholesterol also rises, while LDL cholesterol declines. This explains why women experience an increased risk of heart disease after menopause – as their estrogen levels fall at this point.

Hypothyroidism (decreased production and secretion of thyroid hormones) causes an increase in LDL and total cholesterol levels. Hyperthyroidism (excess production and secretion of thyroid hormone) has the contrary effect. Your level of LDL cholesterol may rise if you undergo an androgen deprivation therapy. Androgen deprivation therapy brings down the level of androgen in the body as a means of stopping the growth of prostate cancer. If you are deficient in growth hormones, your blood LDL levels will also increase.

Nervous system

Cholesterol plays a very important role in the human brain. It is interesting to know that over 25 percent of your body’s cholesterol supply is contained in your brain. This fat is vital for the development of nerve cells as well as their protection. Of course, nerve cells help your body to communicate with each other.

While cholesterol is required for optimal functioning of the brain, excess of it can cause damage. Too much cholesterol in the arteries that supply the brain can result in strokes. A stroke is a disruption to the flow of blood to the brain. It can lead to loss of movement, memory, speech difficulty, and difficulty with swallowing.

High blood cholesterol on its own causes loss of mental function and memory. High blood cholesterol can speed up the formation of beta-amyloid plaques. These plaques are sticky proteins that contribute to Alzheimer’s disease.

Digestive system

Cholesterol is also essential in the functioning of the digestive system. It enhances bile production. Bile helps your body to break down fats and absorb the nutrients. However, if you have a lot of cholesterol in your bile, it will concentrate, and form crystals and then harden into stones. These stones are known as gallstones. Gallstones are usually very painful.

Maintaining your cholesterol level will lower your risk of heart disease and also improve the quality of life you live.

Natural ways to lower your cholesterol

Sometimes, it may be possible to lower your cholesterol levels without medications. For instance, eating nutritious foods, regular exercise, and not smoking can help.

Herbal supplements can also help. We will review the best cholesterol lowering supplement shortly. However, some helpful ones include:

  • Hawthorn
  • Garlic
  • Red yeast rice
  • Astragalus
  • Oat bran (in whole oats and oatmeal)
  • Ground flaxseed 

However, there are varying pieces of evidence supporting these claims. You should also know that the United States Food and Drug Administration has not approved these products for the treatment of high cholesterol. There is a need for more research to treat this condition.

You must consult your doctor before using any nutritional or herbal supplements. Some of these supplements might interact with other drugs.

Dosage for CholesLo

According to the instructions on the pill bottle, you are to take two pills twice daily. The pills should be taken with 8 ounces of food and water. During the first week, take one capsule twice a day so that your system can get used to it. You don’t have to worry about taking it on weekends. CholesLo can be used for 4-6 weeks.

Also, if you fail to see any results after a 2-3-month usage, then increase the dosage to 2 capsules thrice daily (don’t take on weekends). For the records, you get 80 capsules from a bottle.

If you are currently on prescription medications, consult your doctor and get his advice before taking any supplement including CholesLo.

CholesLo is contraindicated in pregnant women or breastfeeding mums, as well as children under 18 years of age.

Where to buy CholesLo

CholesLo is available for purchase on the manufacturer’s official website. It is not available at Walmart or any physical store. Online dealers include Amazon, Bolt Health Supplements, eBay, and Quick2You.com. However, you will get the best price deals only on the manufacturer’s official website.

Because the manufacturer wants you to be satisfied, they have offered a 200% no-risk guarantee on their main website. You will do well to try CholesLo for 90 days to see how well it works. If you’re not satisfied, you can get an RMA number and process a return along with your original receipt. You are entitled to a 200% store credit or an exchange. 

Please note! This does not mean that you will be getting your money back. The store credit can be used to buy another product from the manufacturer.

How much is CholesLo?

There are three pricing options as stated on the website. They are:

  • $49.97 for one bottle
  • $119.91 for 4 bottles (and one free bottle)
  • $174.85 for 7 bottles (2 bottles free).

What to expect from CholesLo

Like other health supplements, the results vary. But you should note that this product does not help with weight management or fat loss. It is not an appetite suppressant, neither does it boost metabolism.

But then, it is a great product considering that it is made with natural ingredients whose effects have been verified by clinical studies as presented on the manufacturer’s website.

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